Wang Yi

author: Time:2023-04-06 Number of hits:

Name

Yi Wang

Title

Professor, Doctoral supervisor


Address

Room 507-2, School of Pharmacitical Science

Tel.

0086-431-85619299

Email

wangyi@jlu.edu.cn


Education Background

1989-1993 Bachlor, Department of Chemistry, Jilin University

1995-1998 Master, Environment Hygiene, Norman Bethune University of medical sciences

1999-2002 Ph.D. , biochemistry and molecular biology, Institute of Frontier Medical Science, Jilin University

Work Experience

2009- Professor & doctoral supervisor, School of Pharmacitical Science, Jilin University

2005- 2008 Vice Professor & master supervisor, School of Pharmacitical Science, Jilin University

2001-2005 Lecturer and Vice Professor & master supervisor, Institute of Frontier Medical Science, Jilin University

1999-2001,Teacher assistant and lecturer , School of Pharmacitical Science, Norman Bethune University of medical sciences

1998-1999 Teacher assistant, School of preventive medicine,

Norman Bethune University of medical sciences

1993-1995 Teacher assistant, School of preventive medicine,

Norman Bethune University of medical sciences

Courses

Cell therapeutics; Medical cell biology;Regenerative medicine;Tissue engineering;

Research Field

Cancer vaccines; Cancer biotherapy; cancer stem cells

Scientific Research Achievements

Publications:

1. Zou M, Yin X, Zhou X, Niu X, Wang Y*, Su M*.Salinomycin-Loaded High-Density Lipoprotein Exerts Promising Anti-Ovarian Cancer Effects by Inhibiting Epithelial-Mesenchymal Transition. Int J Nanomedicine. 2022;17:4059-4071

2. Kang B, Zhang T, Huang K, Wang T, Li Y, Mai Y, Li J, Dang S, Zhang Z, Huang W, Wang J, Gao M, Wang Y*, Pan G*.GFI1 regulates chromatin state essential in human endothelial-to-haematopoietic transition. Cell Prolif. 2022 May;55(5):e13244.

3. Liu K, Gao X, Kang B, Liu Y, Wang D, Wang Y*. The Role of Tumor Stem Cell Exosomes in Cancer Invasion and Metastasis. Front Oncol. 2022;12:836548.

4. Kang B, Cong Z, Duan J, Liu K, Wang Y*. Generation of a GFI1-flag knock-in human embryonic stem cell line using CRISPR-Cas9 technology. Stem Cell Res. 2022 Apr;60:102724.

5. Fu C, Tian G, Duan J, Liu K, Zhang C, Yan W, Wang Y*.Therapeutic Antitumor Efficacy of Cancer Stem Cell-Derived DRibble Vaccine on Colorectal Carcinoma. Int J Med Sci. 2021 Jul 23;18(14):3249-3260.

6. Zhang C, Zhao Y, Yang Y, Zhong C, Ji T, Duan J, Wang Y*. RNAi mediated silencing of Nanog expression suppresses the growth of human colorectal cancer stem cells. Biochem Biophys Res Commun. 2021 Jan 1;534:254-260.

7. Fu C, Xiao X, Xu H, Lu W, Wang Y*.Efficacy of atovaquone on EpCAM+CD44+ HCT-116 human colon cancer stem cells under hypoxia Exp Ther Med. 2020 Dec;20(6):286.

8. Fu C, Zhou N, Zhao Y, Duan J, Xu H, Wang Y. Dendritic cells loaded with CD44+ CT-26 colon cell lysate evoke potent antitumor immune responses. Oncol Lett. 2019 Dec;18(6):5897-5904.

9. Fu C, Wang L, Tian G, Zhang C, Zhao Y, Xu H, Su M, Wang Y*. Enhanced anticancer effect of oncostatin M combined with salinomycin in CD133+ HepG2 liver cancer cells. Oncol Lett. 2019 Feb;17(2):1798-1806.

10. Fu C, Zhou N, Zhao Y, Duan J, Xu H, Wang Y*. Dendritic cells loaded with CD44+ CT-26 colon cell lysate evoke potent antitumor immune responses. Oncol Lett. 2019 Dec;18(6):5897-5904.

11. Zhang C, Chen W, Zhang X, Zheng Y, Yu F, Liu Y, Wang Y*. Grape seed proanthocyanidins induce mitochondrial pathway-mediated apoptosis in human colorectal carcinoma cells. Oncol Lett. 2017 Nov;14(5):5853-5860.

12. Zhihua Cheng, Zhenshengnan Li, Ke Ma, Xiaoyu Li, Nan Tian, Jinyue Duan, Xu Xiao, and Yi Wang*. Long Non-coding RNA XIST Promotes Glioma Tumorigenicity and Angiogenesis by Acting as a Molecular Sponge of miR-429. J Cancer. 2017; 8(19): 4106–4116.

13. Zhang C, Gong P, Liu P, Zhou N, Zhou Y, Wang Y*. Thioridazine elicits potent antitumor effects in colorectal cancer stem cells. Oncol Rep. 2017;Feb 37(2):1168-1174

14. Teng saying, Wang Yi, Li Pingya, Liu Jinhua, Wei Anhui, Wang Haotian, Meng Siangkun, Pan Di and Zhang Xinmin*. Effects of R type and S type ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells. Molecular Medicine Reports, 2017 Apr;15(4):2029-2038

15. Zhang C, Miyatake H, Wang Y, Inaba T, Wang Y, Zhang P, Ito Y*. A Bioorthogonal Approach for the Preparation of a Titanium-Binding Insulin-like Growth-Factor-1 Derivative by Using Tyrosinase. Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11447-51.

16. Zhang C, Tian Y, Song F, Fu C, Han B, Wang Y*. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Nov;34(5):2469-76.

17. Xiaoyue Zhou, Shin-Hye Park, Hongli Mao, Takashi Isoshima, Yi Wang, and Yoshihiro Ito. Nanolayer formation on titanium by phosphonated gelatin for cell adhesion and growth enhancement. Int J Nanomedicine. 2015 Sep 2;10:5597-607.

18. Yue Zhou, Hongli Mao, Binata Joddar, Nobuhisa Umeki, Yasushi Sako, KenIchi Wada, Chieko Nishioka, Eiki Takahashi, Yi Wang & Yoshihiro Ito*. The significance of membrane fluidity of feeder cell-derived substrates for maintenance of iPS cell stemness. Scientific Reports 2015 Jun 12;5:11386

19. Changhao Fu, Zi Yan, Hao Xu, Chen Zhang, Qi Zhang, Anhui Wei, Xi Yang and Yi Wang*. Isolation, identification and differentiation of human embryonic cartilage stem cells. Cell Biology International. Cell Biol Int. 2015 Jul;39(7):777-87.

20. Wenji Sun#, Yi Wang#; James E East; Amy Kimball; Katherine Tkaczuk; Susan Kesmodel; Scott E Strome; Tonya J. Webba*Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional. Cytokine 2015;72(1):48-57 (#: co-first author)

21. Fuqiang Zhang, Feng Hao, Dong An, Linlin Zeng, Yi Wang, Xuemin Xu, and Mei-Zhen Cui*. Matricellular Protein Cyr61 Is a Key Mediator of Platelet-derived Growth Factor-induced Cell Migration. J Biol Chem. 2015 Mar 27;290(13):8232-42.

22. Pengfei Liu#, Yetong Feng#, Yi Wang1*, Yulai Zhou1*. Therapeutic action of bone marrow-derived stem cells against acute kidney injury. Life Sciences. 2014 Oct 12;115(1-2):1-7.

23. Pengfei Liu, Yetong Feng, Chao Dong, Dandan Yang2, Bo Li, Xin Chen, Zhongjun Zhang, Yi Wang*, Yulai Zhou*, Lei Zhao*Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy . PLoS ONE 2014; 9(5): e97123.

24. Cong Zhong-Yi, Lin Shuang-Shen, Cong Deng-Li, Su Xiao-Yun, Wang Yi, Zhou Yu-Lai. Effect of Ginsenoside Rh3 on Proliferation and Apoptosis of Human Colon Carcinoma Cells. Chinese Journal of Gerontology, 2010; 30(18):2644-6

25. Bo Han, Yiwen Jiang, Chen Zhan, Yue Zhou, Yi Wang*. The Effect of 20( S ) - Ginsenoside Rg3 on the Proliferation and Apoptosis of colon cancer stem cells in vitro. 2012; 32(20): 4431-3

26. Xu YY, Chen Y, Wang Y*. Progress in cancer stem cell research, Chinese Journal of Gerontology, 2009;29(11):2823-5

27. WANG Yi, WANG Fang, ZHAO Hong-Yu, et al. Prostatic acid phosphatase: new immunotherapeutic target of colon adenocarc inoma. Chinese Journal of Gerontology, 2008;28(18):1804-7

28. WANG Yi, Takao Y, Harada M, et al. New epitope peptides derived from Hepatitis C virus (HCV) 2a which have the capacity to induce cytotoxic T lymphocytes in HLA-A2+ HCV-infected patients. Microbiol Immunol. 2006;50(11):857-65.

29. WANG Yi, Takao Y, Harada M, et al. Identification of hepatitis C virus (HCV) 2a-derived epitope peptides having the capacity to induce cytotoxic T lymphocytes in human leukocyte antigen-A24(+) and HCV2a-infected patients. Cell Immunol. 2006;241(1):38-46.

30. WANG Yi, Harada M, Yano H, et al. Prostate-specific antigen-reactive cytotoxic T lymphocyte precursors in colon cancer patients. Oncology Report. 2006;15 (2):317-321.

31. WANG Yi, Harada M, Yano H, et al. Prostatic acid phosphatase as a target molecule in specific immunotherapy for patients with non-prostate adenocarcinoma. Journal of Immunotherapy , 2005;28(6):535-541

32. WANG Yi, Harada M, Yamada A , Itoh K. Expression of prostatic acid phosphatase in a variety of tumor types. Cancer Science, 2004;95: Supplement 294.

33. WANG Yi, SU Xiao-Yun, et al. Induction of specific CTLs in BALB/c mice by chiral MUC1 synthetic peptide Vaccine. J Fourth Mil Med Univ ,2004; 25 (16): 1452-1455.

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